You're doing everything right. So why do you still feel this way?
You're eating well. You're moving your body. You're taking your supplements. And yet. The joint aches are still there. The brain fog lingers. Your skin just doesn't look the way it used to. Your energy fades quickly these days.
Here's what no one tells you: in perimenopause and menopause, rising inflammation may be the hidden variable sabotaging everything else you're doing.
As estrogen shifts, your body's natural anti-inflammatory defenses shift with it. NF-kB, the master switch for inflammation, starts firing more frequently.
And no amount of dieting or yoga fully compensates for that.
Until now.
Meet Radiance Defense Boost
A first-of-its-kind formula built around glucoraphanin: the potent compound found in broccoli sprouts, that activates your body's own NRF2 pathway: your internal antioxidant and anti-inflammatory engine.
Radiance Defense Boost goes upstream, triggering the cellular-level processes that help your body fight inflammation, clear used estrogens, and protect your skin — all at once.
The Science Behind the Sprout
I'll be honest. I didn't fully appreciate the power of broccoli sprouts until I sat down with Dr. Jed Fahey, the Johns Hopkins nutritional biochemist who pioneered sulforaphane research over 30 years ago. What he shared genuinely changed the way I think about cellular health in midlife.
Here's what makes this compound so remarkable...
Broccoli sprouts contain up to 100 times more glucoraphanin than mature broccoli. When glucoraphanin is activated, by an enzyme called myrosinase, it converts into sulforaphane, which Dr. Fahey has called "the most potent natural inducer of chemoprotective enzymes" ever identified.
Sulforaphane works by flipping the switch on NRF2 — a master regulator that controls 200 to 500 antioxidant and detox genes in the body. When NRF2 is activated, your body ramps up its own production of glutathione, your most powerful internal antioxidant. It also activates Phase II detoxification enzymes that help clear used estrogens, xenoestrogens like BPA and phthalates, and other environmental toxins that drive hormonal imbalance.
One clinical study showed sulforaphane reduced urinary toxins by 61%in people living in highly polluted areas.
Another study of women who consumed broccoli sprouts daily showed significant reductions in circulating estrogen compared to controls.
And unlike vitamin C, which clears your body within hours, sulforaphane's effects on these enzyme systems last for days.
It's not a quick hit... It's a sustained cellular upgrade.
For women in menopause, that means support for the estrogen-inflammation cycle at the root level.
What’s Inside and Why It Works
Glucoraphanin
from broccoli sprout extractThe star of the formula. Glucoraphanin activates the NRF2 pathway, simultaneously cranking up antioxidant production and turning down NF-kB — the master switch that drives chronic inflammation. This is the compound researchers have spent decades studying for its role in cancer prevention, cellular protection, hormonal balance, and longevity. One cup of broccoli sprouts delivers what would take roughly 100 cups of mature broccoli to match.
Horseradish Root
This is the activation key that makes glucoraphanin work harder. Horseradish contains its own glucosinolates and supports myrosinase activity — the enzyme that converts glucoraphanin into its active form, sulforaphane. Without this activation step, much of the glucoraphanin you consume passes through unused. Horseradish also brings its own anti-inflammatory isothiocyanates to the formula, amplifying the effect. Think of it as the ingredient that makes everything else more bioavailable.
Vitamin C
Vitamin C is critical for collagen synthesis, which means it works alongside the skin-protective benefits of sulforaphane for a visible inside-out radiance effect. It also supports the liver's ability to process and eliminate used estrogens — complementing the detoxification work the NRF2 pathway is already doing.
Methylated Folate
as 5-mthfMost folate supplements contain folic acid — the synthetic form that a significant percentage of women can't properly convert into a usable form in the body. Up to 40% of the population carries a variation of the MTHFR gene that impairs this conversion, meaning they're taking folate and getting little to none of the benefit.Radiance Defense Boost uses methylated folate — the bioactive, already-converted form known as 5-MTHF — which your body can use immediately, regardless of your genetic makeup.
Why does this matter so much in midlife?
Beyond estrogen clearance, methylated folate supports:
- Healthy homocysteine metabolism — elevated homocysteine is linked to cardiovascular risk and cognitive decline, both of which increase in menopause
- Neurotransmitter production, including serotonin and dopamine — which is why poor methylation so often shows up as mood issues, anxiety, and depression
- DNA repair and cellular integrity — working alongside sulforaphane's NRF2 activation for protection at the deepest cellular level
- Brain health and mental clarity — because a brain that can't methylate efficiently is a brain that struggles to function at its best
If you've ever taken folate and wondered why you didn't feel much difference — this is likely why. The form matters as much as the dose.
A Note for Women with MTHFR
MTHFR is a gene that provides instructions for an enzyme involved in processing folate. When this gene has a variant (which occurs in an estimated 40% of the population) that enzyme doesn't work efficiently. The result is impaired methylation: your body struggles to convert standard folic acid into the active form it can actually use.
Impaired methylation affects:
- Estrogen detoxification: used estrogens recirculate instead of being cleared, worsening hormonal symptoms
- Mood and mental health: serotonin and dopamine production both depend on healthy methylation
- Cardiovascular health: homocysteine builds up when methylation is sluggish, raising inflammation and heart disease risk
- Brain function: memory, focus, and cognitive clarity all take a hit
- Cellular repair: DNA damage goes unaddressed at a higher rate
Because Radiance Defense Boost uses methylated folate in its already-active 5-MTHF form, it bypasses the conversion step entirely. Your body gets what it needs immediately.
If you've been told your folate levels look fine on a blood test but you still don't feel right, impaired methylation may be part of the picture. This formula was designed with you in mind.
What you may notice when you try Radiance Defense Boost
- Reduced joint pain, puffiness, and inflammatory symptoms
- Clearer skin with a visible inside-out glow
- Fewer PMS and menopause struggles, as support for healthy estrogen metabolism and detoxification kicks in
- Better energy and weight loss as inflammation is brought under control
Individual results vary. As with any supplement, consistent daily use over time yields the best results.
Protect the Glow You're Building
One capsule a day activates your body's own cellular defense system. No fading. No gaps. Just consistent support from the inside out.
While You’re Here...
Grab These Bestsellers, Too
Julva®
Intimate skin deserves the same care as the rest of you. Julva's DHEA-powered formula supports vaginal tissue health, moisture, and comfort.
Life Saver
“This product was a huge help when intimacy became really painful after menopause. I would totally recommend!”
— Courtney S.
Mighty Maca® Plus
Mighty Maca supports hormonal balance, energy, libido, and mood. It's a bestseller for good reason. Mix it into your morning smoothie and feel the difference.
Love Love Love
“Mighty maca mango has changed my daily routine! I feel so much healthier and happier!”
— katrina w.
Balance
Balance is your daily foundation. Formulated to support progesterone balance, it's the topical that keeps everything running more smoothly, even when your body is working hard to adjust.
Amazing
“I have tried so many supplements to help me fall asleep and stay asleep. Balance cream has helped me get a good nights sleep. I am so grateful.”
— meg b.
From our founder, triple-board-certified OB-GYN, Dr. Anna Cabeca
"Inflammation doesn't announce itself. It just accumulates in the background, making everything harder in midlife. The symptoms you can't explain, the recovery that takes longer, the skin that looks more tired than you feel.
I developed Radiance Defense Boost because the research on glucoraphanin is genuinely compelling, and because women in midlife deserve a supplement that works at the cellular level, not just on the surface.
This is the formula I wish had existed ten years ago. I hope you love the way this makes you feel."
Less inflammation starts here.
Try Radiance Defense Boost today!
Subscribe & save
Save 14%$50.74
Normal Price:
$59.00Total Savings: $8.26
30 vegetarian capsules
1 month supply
60-day money back guarantee
Supported payment methods:BEST OFFER
$177.00
90 vegetarian capsules
3 month supply
free shipping
60-day money back guarantee
Supported payment methods:most popular
$118.00
60 vegetarian capsules
2 month supply
free shipping
60-day money back guarantee
Supported payment methods:
